CBAC Announcements  



Graduate Student First Author on Paper

A recent paper, “Cardiac Electrophysiologic Substrate Underlying the ECG Phenotype and Electrogram Abnormalities in Brugada Syndrome Patients” has been accepted for publication in the journal Circulation. The paper describes research conducted by Junjie Zhang, a PhD student in Yoram Rudy's lab. Junjie used ECGI to study the arrhythmic substrate in the hearts of 25 patients with a hereditary rhythm disorder, called the Brugada syndrome associated with an increased incidence of sudden death.

Additional authors include CBAC Director Yoram Rudy, members Phillip Cuculich. Jennifer Silva, Daniel Cooper, Mitchell Faddis, alumnus Thomas O'Hara, Frédéric Sacher, Kurt Hoffmayer, Maria Strom, Mélèze Hocini, Michel Haïssaguerre, and Melvin Scheinman.



Medical researchers receive NIH grant for summer institute program

D.C. Rao, PhD, director of the Division of Biostatistics, professor of biostatistics and of biostatistics in genetics and psychiatry at Washington University School of Medicine in St. Louis, and CBAC member Victor G. Davila-Roman, MD, professor of medicine, of anesthesiology and of radiology, have received a four-year, $1.28 million grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH) for a program titled “PRIDE Summer Institute in Cardiovascular Genetic Epidemiology.”


NIH grant to support study of heart’s inner mechanisms

Findings could lead to better treatment for cardiac arrhythmia and long QT syndrome

CBAC member Jianmin Cui, Ph.D. has received a nearly $1.7 million grant from the National Institutes of Health (NIH) to study the molecular bases for the function of potassium channels vital for the heart, brain, inner ear and other tissues.



Wickline receives chancellor’s innovation award

CBAC member Samuel A. Wickline, MD, received the Chancellor’s Award for Innovation and Entrepreneurship at Washington University in St. Louis. Wickline, the James R. Hornsby Family Professor of Biomedical Sciences, was presented with the honor at the Faculty Achievement Awards ceremony.



Phillip Bayly Receives Distinguished Faculty Award

CBAC Member Philip Bayly, PhD, the Lilyan and E. Lisle Hughes Professor of Mechanical Engineering and chair of the Department of Mechanical Engineering & Materials Science in the School of Engineering & Applied Science received the Distinguished Faculty Award. This award recognizes outstanding commitment to the intellectual and personal development of students.



Rudy Receives University of Oxford Visiting Professorship

Yoram Rudy, the Fred Saigh Distinguished Professor of Engineering and CBAC Director, was conferred the title of Visiting Professor in Computational Medicine by the University of Oxford, UK. The appointment is in the Mathematical, Physical and Life Sciences Division, and in the Department of Computer Science. In this capacity, Professor Rudy will deliver lectures and provide guidance to research at Oxford in computational biosciences and cardiac physiology.


George receives grant to study new drugs on heart tissue

As part of a national effort to predict drug safety and effectiveness, CBAC member Steven C. George, MD, PhD, has received a grant from the National Institutes of Health (NIH) to continue developing an integrated in vitro model of perfused tumor and cardiac tissue.

George is chair of the Department of Biomedical Engineering and the Elvera & William Stuckenberg Professor of Technology & Human Affairs.



Wang receives prestigious NIH BRAIN initiative award

CBAC member, Lihong Wang, PhD, has received a prestigious BRAIN Initiative Award from the National Institutes of Health (NIH).



Damiano named chief of cardiothoracic surgery

CBAC member, Ralph J. Damiano Jr., MD, has been named chief of the Division of Cardiothoracic Surgery at Washington University School of Medicine in St. Louis.



Mann Elected Member of the Association of American Physicians

Douglas Mann, MD was elected to membership in the prestigious Association of American Physicians at its annual meeting on April 25 - 27 in Chicago. Each year, individuals having attained excellence in achieving pursuit of medical knowledge, and the advancement through experimentation and discovery of basic and clinical science and their application to clinical medicine, are recognized by nomination for membership by the Council of the Association.


Rudy Awarded $1.52M NIH Grant

Dr. Yoram Rudy, The Fred Saigh Distinguished Professor and Director, Cardiac Bioelectricity and Arrhythmia Center was awarded a $1,520,000 four year grant (years 21-24 of the award) from the NIH – National Heart, Lung and Blood Institute for the project titled “Cardiac Excitation and Arrhythmias.” The overall objective of this research is to provide mechanistic understanding of the relationships between the dynamic molecular structure of cardiac ion-channel proteins during their gating process and their function as charge carriers during the whole-cell action potential (AP).


Jay Receives $400K Established Investigator Award

Patrick Jay, MD, PhD, received the Established Investigator Award by the American Heart Association (AHA), a $400,000 five-year award, for the project titled, “Maternal Age: A Modifiable Risk Factor for Congenital Heart Disease”


Rudy gives keynote address in Milan, Italy

Dr. Yoram Rudy, The Fred Saigh Distinguished Professor and Director, Cardiac Bioelectricity and Arrhythmia Center gave the keynote address entitled:“Mechanisms of Human Cardiac Arrhythmias: Noninvasive Studies with Electrocardiographic Imaging (ECGI)" at the University of University of Milano Department of Biotechnology and
Biosciences, Department Day Celebration (December 5, 2013).


Wang wins IEEE Biomedical Engineering Award

Lihong Wang, PhD, will receive the 2014 IEEE Biomedical Engineering Award, the highest honor conferred by the Instituteof Electrical and Electronics Engineers (IEEE) in this field.



Three medical faculty named Wolff professors

CBAC member, Daniel S. Ory, MD, was named Edith L. Wolff Professor of Cardiology. He was one of three faculty that received this professorship in their respective fields.



Rudy gives keynote addresses in Scotland and England

Dr. Yoram Rudy, The Fred Saigh Distinguished Professor and Director, Cardiac Bioelectricity and Arrhythmia Center gave the keynote address entitled:“Noninvasive Mapping of Human Cardiac Arrhythmias with ECGI”, at the 40th International Congress on Electrocardiology (August 7-10, 2013).

Full Program

He also gave the keynote address while he was a Visiting Fellow at Oxford University, UK (August 11-24, 2013) entitled: “Electrocardiographic Imaging of Cardiac Electrophysiology and Arrhythmia”, at the “Computer Science Meets Cardiology” Symposium (August 20th, 2013).

Full Program


Wickline named Hornsby Family Professor of Biomedical Sciences

Samuel A. Wickline, MD, has been named the inaugural James R. Hornsby Family Professor of Biomedical Sciences



Nerbonne to lead Center for Cardiovascular Research

Jeanne M. Nerbonne, PhD, the Alumni Endowed Professor of Molecular Biology and Pharmacology, has been named director of the Center for Cardiovascular Research.



Rudy gives keynote address at the Symposium in Honor of David S. Rosenbaum, M.D.

Dr. Yoram Rudy, The Fred Saigh Distinguished Professor and Director, Cardiac Bioelectricity and Arrhythmia Center gave the keynote address entitled: "Cardiac Repolarization: From Molecule to Human Heart"



Nehorai awarded $750,000

Arye Nehorai, PhD, chair of the Department of Electrical and Systems Engineering and the Eugene and Martha Lohman Professor of Electrical Engineering, received a five-year, $750,000 grant from the Office of Naval Research for research titled “Co-Prime Sensor Array Signal Processing.”


Nichols awarded $1.9 million

Colin G. Nichols, PhD, the Carl F. Cori Professor and professor of cell biology and physiology, has received a five-year, $1.9 million grant renewal from the National Heart, Lung, and Blood Institute for research titled “SUR1 (ABCC8) and Atrial KATP Channels.”


Nerbonne and Herzog awarded $288,800

CBAC member Jeanne Nerbonne, PhD, Alumni Endowed Professor of Developmental Biology in the Division of Biology & Biomedical Sciences at the School of Medicine, and Erik Herzog, PhD, professor of biology in Arts & Sciences, received a $288,800 grant from the National Institutes of Health for research titled “Neuronal Excitability in the Regulation of Circadian Rhythms.” They also could receive a renewal grant of equal amount in each of the next three years.


Graduate students receive prize

Smiruthi Ramasubramanian and Jiajing Xu, graduate students in Dr. Yoram Rudy's laboratory, received a Merit Award for their poster presentation “Structure and Gating of the Cardiac Iks Channel” at the 10th Gordon Research Conference on Cardiac Arrhythmia Mechanisms (Ventura, California, February 21st, 2013).


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