Ion channels are the molecular basis of membrane excitability in all cell types, including neuronal, heart, and muscle cells. This course presents the structure and the mechanism of function of ion channels at the molecular level. It introduces the basic principles and methods in the ion channel study as well as the structure-function relation of various types of channels. Exemplary channels that have been best studied will be discussed to illustrate the current understanding.

The goal of this course is to provide working knowledge of theoretical methods that are used in the fields of Electrophysiology and Bioelectricity. The methods will be applied to describe, from a theoretical and quantitative perspective, the electrical behavior of excitable tissues, with emphasis on the heart. Topics to be covered include: Action potential generation, action potential propagation, source-field relationships in homogeneous and inhomogeneous media, models of cardiac excitation and arrhythmia, quantitative electrocardiography. Discussion sessions will covers key papers in the fields of cardiac electrophysiology, cardiac arrhythmia, electrocardiography and electrocardiographic imaging.

This course integrates and extends the basic principles of cell biology and physiology to the functions of the major organ systems of the body i.e. muscle, cardiovascular, renal, respiratory, gastrointestinal and endocrine.

This is a core course for incoming graduate students in Cell and Molecular Biology programs to learn about research and experimental strategies used to dissect molecular mechanisms that underlie cell structure and function, including techniques of protein biochemistry.

The purpose of this course is to introduce the basic concepts of mathematical physics to students in the context of problems they are likely to encounter in their coursework and research. Specifically, the course will introduce analytical and numerical mathematical methods relevant to the fields of biophysics and biochemistry. By the end of the course, the students should have a good grasp of these basic techniques, their application to biological problems, and related software and computational resources.

This course focuses on genome sequence analysis, emphasizing computational and algorithmic issues. Topics covered include: the essential biology, the essential probability theory, base calling and quality clipping, predicting protein-coding genes (including Hidden Markov Models and comparative genomics approaches), sequence aligning, RNA folding, protein domain analysis, and an introduction to population biology. This includes both paper and pencil homework assignments and programming labs in "C."

The goal of the course is to provide a foundation for understanding the molecular determinants of protein structure, sequence-structure relationships, protein evolution, and protein design. The course will be divided into three modules namely 1) Quantitative understanding of protein structures and sequence-structure relationships; 2) Protein Stability; and 3)Protein folding and design.

This course focuses on the analysis of blood flow through the heart and blood vessels. Basic cardiovascular anatomy and physiology; principles of continuum mechanics. Flow through heart chambers, valves, and coronary arteries; peristaltic flow in the embryonic heart. Steady and unsteady flow in tubes; wave propagation in blood vessels; flow in collapsible tubes (veins); microcirculation.