CBAC Cardiac Bioelectricity and Arrhythmia Center Mission  

CBAC Mission

The Cardiac Bioelectricity and Arrhythmia Center, CBAC, is an interdisciplinary center whose goals are to study the mechanisms of rhythm disorders of the heart (cardiac arrhythmias) and to develop new tools for their diagnosis and treatment. Cardiac arrhythmias are a major cause of death (over 300,000 deaths annually in the US alone; estimated 7 million worldwide) and disability, yet mechanisms are poorly understood and treatment is mostly empirical. Through an interdisciplinary effort, CBAC investigators apply molecular biology, ion-channel and cell electrophysiology, optical mapping of membrane potential and cell calcium, multi-electrode cardiac electrophysiological mapping, Electrocardiographic Imaging (ECGI) and other noninvasive imaging modalities, and computational biology (mathematical modeling) to study mechanisms of arrhythmias at all levels of the cardiac system. Our mission is to battle cardiac arrhythmias and sudden cardiac death through scientific discovery and its application in the development of mechanism-based therapy.

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