CBAC Member Jonathan Moreno conducts cardiac research in Jon Silva’s lab in biomedical engineering.
Moreno seeks precision medicine for genetic heart condition (Links to an external site)
Tag: Jonathan Silva
SentiAR raises $5.1 million for holographic cardiac ablation guidance system (Links to an external site)
Technology allows electrophysiologists to visualize cardiac anatomy in hands-free, real-time 3D. This article features CBAC members Jonathan Silva and Jennifer Silva.
WashU-developed holograms help physicians during cardiac procedure (Links to an external site)
Holographic display improves physician accuracy when treating irregular heartbeat. CBAC members, Jennifer N. Avari Silva, MD, associate professor of pediatrics at the School of Medicine, and Jonathan Silva, associate professor of biomedical engineering in the McKelvey School of Engineering, co-led a team that tested a Microsoft HoloLens headset with custom software during cardiac ablation procedures on patients at St. Louis Children’s Hospital.
Heart’s electrical propagation focus of WashU interdisciplinary study (Links to an external site)
CBAC members, Jon Silva’s and Jeanne Nerbonne’s lab will investigate a novel protein component of the cardiac sodium channels to determine its functional effects in the physiological regulation and pathophysiological remodeling of electrical propagation of the heart.
New model of irregular heartbeat could boost drug efficacy (Links to an external site)
Patients with irregular heartbeats, or arrhythmia, have few effective treatment options — available drugs are not always effective, and implanted defibrillators can be too aggressive.
This article features the work of CBAC member Jonathan Silva, PhD, Associate Professor of Biomedical Engineering.
A sodium surprise (Links to an external site)
Engineers find unexpected results during cardiac research. This article features CBAC members Jonathan Silva, assistant professor of biomedical engineering, and Jeanne Nerbonne, Alumni Endowed Professor of Molecular Biology and Pharmacology and director of the Center for Cardiovascular Research at Washington University’s School of Medicine.
Silva, Nerbonne and Zoltan Varga from the University of Debrecen in Hungary worked with collaborators to take a closer look at the sodium ion channels responsible for creating the electrical signal that makes the heartbeat.They found that certain sodium subunits attached to the main protein in different places. It was an unexpected result that could lead to better drug delivery and efficacy for patients with heart arrhythmia.
Common heart ailment target of new research (Links to an external site)
Jon Silva and his team will study how small molecules and proteins interact with ion channels in the heart to cause and prevent arrhythmia, when the heart beats too fast, too slow, or is too unstable