Optical coherence tomography shows beating, development in human heart model (Links to an external site)
Imaging in Chao Zhou’s lab is promising method to study heart development, disease
Popular heart failure drug no better than older drug in sickest patients (Links to an external site)
Study suggests older drug may be safer for an advanced form of heart failure. Article features CBAC member Douglas L. Mann, the Tobias and Hortense Lewin Professor of Medicine.
Radiation therapy reprograms heart muscle cells to younger state (Links to an external site)
Radiotherapy repairs irregular rhythms in those with life-threatening heart arrhythmia.
New research from Washington University School of Medicine in St. Louis suggests that radiation therapy can reprogram heart muscle cells to what appears to be a younger state, fixing electrical problems that cause a life-threatening arrhythmia without the need for a long-used, invasive procedure.
Distilling 70 years’ worth of data (Links to an external site)
Jonathan Silva and his lab use computational biology to better understand fundamentals of arrhythmia
Potential mechanical triggers behind inherited heart disease focus of new study (Links to an external site)
CBAC member Nathaniel Huebsch receives nearly $2 million NIH grant to research the role that blood pressure plays in triggering symptoms in patients with hypertrophic cardiomyopathy.
Variations in sodium channel molecular composition may be behind drug efficacy (Links to an external site)
Silva, Nerbonne labs investigate accessory proteins in steps toward precision medicine
Compound may prevent risk of a form of arrhythmia from common medications (Links to an external site)
CBAC Jianmin Cui leads a multi-institutional team to make this discovery. Dozens of commonly used drugs, including antibiotics, antinausea and anticancer medications, have a potential side effect of lengthening the electrical event that triggers contraction, creating an irregular heartbeat, or cardiac arrhythmia called acquired Long QT syndrome. While safe in their current dosages, some of these drugs may have a more therapeutic benefit at higher doses, but are limited by the risk of arrhythmia.
Moreno seeks precision medicine for genetic heart condition (Links to an external site)
CBAC Member Jonathan Moreno conducts cardiac research in Jon Silva’s lab in biomedical engineering.
SentiAR raises $5.1 million for holographic cardiac ablation guidance system (Links to an external site)
Technology allows electrophysiologists to visualize cardiac anatomy in hands-free, real-time 3D. This article features CBAC members Jonathan Silva and Jennifer Silva.
Ghiska Ramahdita becomes finalist in Reach Out SciComm Slam (Links to an external site)
Ghiska Ramahdita, a doctoral student in the labs of CBAC member Nathaniel Huebsch and Guy Genin, will continue on to compete in the finals May 4, 2021